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Contrast Agent Diatrizoic Acid Dihydate Sodium Amidotrizoate CAS No 50978-11-5

Minimum Order Quantity : 50 kg Price : to be negotiated
Packaging Details : 50kg in a fiber drum (350cm*580cm) Delivery Time : 10 working days
Payment Terms : T/T, L/C Supply Ability : 50000 kg per year
Place of Origin: China Brand Name: LIBANG
Certification: Chinese GMP

Detail Information

Quality Specification: USP, EP, CP Certification: Chinese GMP
Dossier: DMF Available Batch Size: Approx. 500kg
Storage: Store At Room Temperature. HS Code: 2924.2990 99
High Light:

Contrast Agent Diatrizoic Acid Dihydate

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CAS No 50978-11-5 Diatrizoic Acid Dihydate

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Sodium Amidotrizoate CAS No 50978-11-5

Product Description

 Diatrizoic Acid API USP EP Amidotrizoic Acid Dihydate CAS No. 50978-11-5 Contrast Agent

 

Chemical name: Benzoic acid, 3,5-bis(acetylamino)-2,4,6-triiodo-.3,5-Diacetamido-2,4,6-triiodobenzoic acid

Solubility: Very slightly soluble in water; soluble in ammonia solution or sodium hydroxide solution.

Fuction: Amidotrizoic Acid Dihydate is used for producing the radiopaque contrast agent for intravascular use named as Diatrizoate Meglumine and Diatrizoate Sodium Injection or Diatrizoate Meglumine Injection.

Advantage: Control the Free aromatic amine limit within a lower acceptance criteria. 

 

Diatrizoate, also known as amidotrizoate, is a contrast agent used during X-ray imaging. This includes visualizing veins, the urinary system, spleen, and joints, as well as computer tomography (CT scan). It is given by mouth, injection into a vein, injection into the bladder, through a nasogastric tube, or rectally.

Relatively common side effects include vomiting, diarrhea, and skin redness. Other side effects include itchiness, kidney problems, low blood pressure, and allergic reactions. It is not recommended in people who have an iodine allergy. Diatrizoate is an iodinated ionic radiocontrast agent with high osmolality.

Diatrizoate was approved for medical use in the United States in 1954. It is on the World Health Organization's List of Essential Medicines.

 

Xi'an Libang Pharmaceutical Co.,Ltd has developed Diatrizoic Acid API since 2003, as its biggest manufacturer in China.

The typical quality attributes for Diatrizoic Acid as follow:

 

TEST SPECIFICATION RESULT
Ethyl alcohol NMT 0.5% Not detected
Acetic acid NMT 0.5% Not detected
Bacterial endotoxins NMT 1.5 EU/g <1.5 EU/g
Microbial Limit Total aerobic microbial count: <1000 cfu/g Conforms
Total yeast and molds count: <100 cfu/g Conforms
Assay 98.0%~102.0%(Calculated on the anhydrous basis) 99.2%

 

Contrast Agent Diatrizoic Acid Dihydate Sodium Amidotrizoate CAS No 50978-11-5 0

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